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Perlane Frequently Asked Questions

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What is Perlane?

Perlane is a transparent hyaluronic acid gel that is injected into facial tissue to smooth wrinkles and folds, especially around the nose and mouth (nasolabial folds). Perlane is made of non-animal-based hyaluronic acid, a natural substance that is produced naturally by the human body.

What is a Perlane injection?

Your skin is made of two layers, with supporting columns holding them apart. The area in-between the two layers of skin includes the clear-jelly like substance hyaluronic acid. While young, the hyaluronic acid is in abundance. As you grow older, the acid between these layers diminishes, and the skin somewhat caves, causing a wrinkle along the line. The wrinkle would be gone if you filled that area back up with the hyaluronic acid, jelly-like substance. That's where Perlane come in. Perlane is injected into the skin with a very thin needle. To restore the natural volumes underneath the wrinkle. The wrinkle is now lifted up and smoothed out. All of this takes about 30 minutes, leaves no marks or scars, and the results can be seen immediately.

Depending on the results you'd like, you can discuss maintenance with your doctor and the period between injections. Follow up injections typically need less Perlane to achieve the results you want. Time between injections is typically 6 to 12 months.

Perlane maintains its shape using the body's own moisture. The hyaluronic acid in Perlane is hydrophilic or "water loving." As hyaluronic acid gradually degrades, each molecule binds to more water and over time, the same volume can be maintained with less hyaluronic acid. This ability of hyaluronic acid to bind to water is what helps provide long-lasting results.

Unlike other hyaluronic acid-based products, such as those made from rooster combs, only Perlane is non-animal-based. This quality virtually eliminates any risk of animal-based disease transmission or allergic reaction.

Where can Perlane be used?

Hyaluronic acid implantation can be used to improve the skin's contour and reduce depressions in the skin due to scars, injury or lines.

Facial lines and features that can be corrected using hyaluronic acid implantation:

  • Worry lines that run across the forehead (forehead lines)
  • Crow's feet at the corner of the eyes (periorbital lines)
  • Frown lines that run between the eyebrows (glabellar lines)
  • Smoker's lines which are vertical lines on the mouth (perioral lines)
  • Marionette lines at the corner of the mouth (oral commissures)
  • Deep smile lines that run from side of the nose to corners of the mouth (nasolabial furrows)
  • Cheek depressions
  • Redefining lip border
  • Acne scars
  • Some facial scars
How long will my treatment take?

Treatment times typically range from 30 to 45 minutes.

What will it accomplish?

Perlane will help smooth moderate to severe facial wrinkles and folds. In a clinical study most patients needed one injection to achieve optimal wrinkle smoothing; about one-third of patients needed more than one injection to get a satisfactory result. The smoothing effect lasted about six months.

How long will Perlane last?

Perlane dissolves and is absorbed by your body over time. Your results will depend on several factors including your skins structure, your lifestyle, and your age.

Most people choose to repeat Perlane treatment from nine months to a year after wrinkle treatment and within six to nine months after lip enhancement.

Are there any potential side effects?

After receiving a Perlane injection some common side effects may be pain, redness, swelling, itching, discoloration, and tenderness at the point of injection. These side effects typically subside within two days of the Perlane injection procedure.

While more severe reactions are rare, occuring in only 1 of 2000 patients on average, some have experienced localized swelling at the injection point, thought to be brought on by hypersensitivity.Tenderness, redness, and very rarely acne-like formations have appeared.

Reactions can typically occur only a few days after the injection, or as long as four weeks. When a reaction does occur, its average lifespan is only a few weeks, and is typically described as moderate and mild.

When should it not be used?

Perlane should not be used in patients who have:

  • Severe allergies marked by a history of anaphylaxis (hypersensitivity to the ingestion or injection of a drug or protein)
  • Multiple severe allergies
  • Severe allergies to gram-positive bacterial proteins

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